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Ted Steele : ウィキペディア英語版
Edward J. Steele
Edward (Ted) J. Steele is an Australian molecular immunologist formerly with the University of Wollongong, now listed as a visiting fellow at Murdoch University. Steele's research has led a resurgent interest in the French scientist Jean-Baptiste de Lamarck, the man who developed the first theory of evolution, pre-dating Charles Darwin by fifty years. Steele was also the subject of a dispute with the University of Wollongong, which led to his widely publicized dismissal, court-ordered reinstatement and subsequent undisclosed financial settlement by the university.
==Scientific interests==
Ted Steele developed the theory of reverse transcription from the somatic (body) cells to the germline (reproductive) cells. This reverse transcription process enables characteristics or bodily changes acquired during a lifetime to be written back into the DNA and passed on to subsequent generations. This is what used to be known as neo-Lamarckism.〔(The implications of Steele's soma-to-germline feedback for the safety of somatic gene therapy in humans )〕 Steele's hypothesis provided the first mechanism to explain Lamarckian evolution: when successful somatic cell changes occur due to environmental changes, copies of the copious new messenger-RNA that have been produced by the successful cells are picked up by harmless retroviruses acting as gene shuttles and transported across the tissue barrier – the Weismann Barrier – to the germline. Finally, the new genetic information is integrated into the DNA by a process involving reverse transcription.
This process of writing or translating new information into the DNA provides the essential precursor to acquired changes being passed on to progeny; to the next generation, thereby demonstrating Lamarckian inheritance of acquired characters. Darwinian natural selection then goes to work on the progeny and subsequent generations: those fit for survival do so and those not fit die out. This recombination of Darwin and Lamarck by Steele has been described as meta-Lamarckism.〔(Meta-Lamarckism is introduced in the book ''Lamarck's Evolution: two centuries of genius and jealousy'' )〕
During the 1980s and 1990s Ted Steele clashed with the scientific establishment, particularly in the UK, over this hypothesis and his support for Lamarck's place in modern science. Steele has stated publicly in an interview with the ABC program ''Lateline'' that his controversial theories have had a strong impact on his career "To be branded a heretic and a pariah meant that my career to keep doing research in this area were extremely limited."〔(Interview on ABC Lateline )〕
His book, ''Lamarck's Signature'' was variously praised and criticized by the scientific mainstream.〔(Robyn Williams Interview with Ted Steele )〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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